TY - CONF T1 - A DNA-Based Archival Storage System Y1 - 2016 A1 - Bornholt, James A1 - Lopez, Randolph A1 - Carmean, Douglas M. A1 - Ceze, Luis A1 - Seelig, Georg A1 - Strauss, Karin AB -

Demand for data storage is growing exponentially, but the capacity of existing storage media is not keeping up. Using DNA to archive data is an attractive possibility because it is extremely dense, with a raw limit of 1 exabyte/mm3 (109 GB/mm3), and long-lasting, with observed half-life of over 500 years. This paper presents an architecture for a DNA-based archival storage system. It is structured as a key-value store, and leverages common biochemical techniques to provide random access. We also propose a new encoding scheme that offers controllable redundancy, trading off reliability for density. We demonstrate feasibility, random access, and robustness of the proposed encoding with wet lab experiments involving 151 kB of synthesized DNA and a 42 kB random-access subset, and simulation experiments of larger sets calibrated to the wet lab experiments. Finally, we highlight trends in biotechnology that indicate the impending practicality of DNA storage for much larger datasets.

PB - ACM CY - New York, NY, USA SN - 978-1-4503-4091-5 UR - https://homes.cs.washington.edu/~luisceze/publications/dnastorage-asplos16.pdf IS - Proceedings of the Twenty-First International Conference on Architectural Support for Programming Languages and Operating System ER -